Diabetic autonomic neuropathy and bladder function: pharmacological use of gangliosides and insulin

This paper briefly describes experimental evidence indicating that bladder dysfunction observed in diabetic rats is due in part to hyperdiuresis and in part to autonomic nerves alterations. The latter, in analogy with somatic nerves alteration, can be ameliorated by treatment of diabetic animals with gangliosides. The use of this agent in the autonomic nerve dysfunction of diabetic origin is discussed.