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Detection and Isolation of Campylobacter spp. from Raw Meat
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Interaction effects between sender and receiver processes in indirect transmission of Campylobacter jejuni between
Bram A D van Bunnik1, Thomas J Hagenaars, Nico M Bolder
1Central Veterinary Institute of Wageningen UR, P,O, Box 65, Lelystad, AB, 8200, The Netherlands. Bram.vanbunnik@wur.nl
BMC Veterinary Research
|July 27, 2012
Summary
Acidifying drinking water significantly reduced Campylobacter jejuni transmission between broiler chickens. This intervention proved effective when applied to both infectious "senders" and susceptible "receivers," lowering infection rates.
Area of Science:
- Veterinary Science
- Microbiology
- Epidemiology
Background:
- Indirect transmission of infectious diseases is common in animals, occurring via environmental routes rather than direct contact.
- Campylobacter jejuni (C. jejuni) transmission between broiler chickens was studied as a model for indirect disease spread.
- Indirect transmission involves three stages: excretion by an infectious sender, environmental transport, and colonization of a susceptible receiver.
Purpose of the Study:
- To experimentally investigate the mechanisms of indirect transmission of C. jejuni between spatially separated broiler chickens.
- To evaluate the impact of modulating the 'sender' and 'receiver' stages on C. jejuni transmission rates.
- To assess the efficacy of acidifying drinking water as a strategy to control indirect disease transmission.
Main Methods:
- Four groups of broiler chickens were established: one control and three treatment groups.
- Treatments involved acidifying the drinking water for inoculated 'sender' birds, susceptible 'receiver' birds, or both.
- Cloacal swabs were collected daily to monitor C. jejuni colonization in all birds.
Main Results:
- A significant decrease in C. jejuni colonization was observed in all treatment groups compared to the control group (p < 0.01).
- In the control group, 12 out of 40 birds became colonized, while only 3 out of 40 birds in each treatment group were colonized.
- A significant negative interaction effect was noted when both sender and receiver groups received acidified water (p = 0.01).
Conclusions:
- Acidification of drinking water significantly reduces the indirect transmission rate of C. jejuni in broiler chickens.
- The intervention is effective when applied to either the infectious source (sender) or the susceptible population (receiver).
- Simultaneous acidification for both senders and receivers showed a pronounced reduction, potentially due to bacterial selection at the sender stage.
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