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Updated: May 20, 2026
07:12
Chronic Post-Ischemia Pain Model for Complex Regional Pain Syndrome Type-I in Rats
Published on: January 21, 2020
[Diagnostic guidelines for complex regional pain syndrome].
E Peltz1, F Seifert, C Maihöfner
1University of Erlangen, Department of Neurology, Erlangen.
Handchirurgie, Mikrochirurgie, Plastische Chirurgie : Organ Der Deutschsprachigen Arbeitsgemeinschaft Fur Handchirurgie : Organ Der Deutschsprachigen Arbeitsgemeinschaft Fur Mikrochirurgie Der Peripheren Nerven Und Gefasse : Organ Der V
|July 27, 2012
Summary
Complex Regional Pain Syndrome (CRPS) is neuropathic pain following limb trauma, presenting with varied symptoms. Diagnosis relies on clinical signs and IASP criteria, supported by imaging and tests, though none are definitive.
Area of Science:
- Neurology
- Pain Medicine
Context:
- Complex Regional Pain Syndrome (CRPS) is a challenging neuropathic pain condition.
- It often develops after minor trauma to the extremities.
- CRPS is characterized by disproportionate pain and diverse sensory, vasomotor, sudomotor, and motor changes.
Purpose:
- To review diagnostic criteria and supportive tools for Complex Regional Pain Syndrome.
- To highlight the importance of clinical assessment and the International Association for the Study of Pain (IASP) criteria.
- To discuss the utility and limitations of various diagnostic modalities.
Summary:
- CRPS diagnosis lacks a definitive gold standard, relying on patient history and clinical presentation.
- The International Association for the Study of Pain (IASP) provides operational diagnostic criteria with good sensitivity and specificity.
- Diagnostic aids include X-ray, MRI, bone scintigraphy, electrophysiology, infrared thermography, and quantitative sensory testing.
Impact:
- Accurate diagnosis of CRPS is crucial for timely and effective treatment.
- Understanding the range of symptoms and diagnostic limitations aids clinicians.
- Objective diagnostic tools can help objectify therapeutic effects and guide patient management.
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