Search research articles

ABOUT JoVE

Overview Leadership Blog JoVE Help Center

AUTHORS

Publishing Process Editorial Board Scope & Policies Peer Review FAQ Submit

LIBRARIANS

Testimonials Subscriptions Access Resources Library Advisory Board FAQ

RESEARCH

JoVE Journal Methods Collections JoVE Encyclopedia of Experiments Archive

EDUCATION

JoVE Core JoVE Business JoVE Science Education JoVE Lab Manual Faculty Resource Center Faculty Site

Terms & Conditions of Use

Related Concept Videos

Psychosurgery

Psychosurgery

Psychosurgery, the surgical alteration or permanent removal of brain tissue to alleviate severe psychological conditions, stands as one of the most radical and controversial treatments in the history of mental health care. Its development and application have evolved significantly, marked by dramatic shifts in scientific understanding and ethical perspectives.
Historical Development of Psychosurgery
In the 1930s, Portuguese neurologist Antonio Egas Moniz introduced a surgical procedure designed...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by

Same author

The clinical picture of symptomatic Rathke cleft cysts in children.

Journal of pediatric endocrinology & metabolism : JPEM·2026

Same author

Consensus on acromegaly complications: an update.

Pituitary·2026

Same author

Pituitary adenoma imaging as a determinant of acromegaly diagnosis and outcomes.

The Journal of clinical endocrinology and metabolism·2026

Same author

Long-term safety and efficacy of pegvisomant monotherapy for acromegaly: final data from the full ACROSTUDY cohort.

Pituitary·2026

Same author

Giant pituitary adenomas: an institutional experience with 289 surgically treated patients.

Acta neurochirurgica·2026

Same author

Risk of recurrence after successful surgery for Cushing's disease and association with USP8 genotype and tumour size: an international, retrospective, longitudinal cohort study.

The lancet. Diabetes & endocrinology·2026

Same journal

Gauze swabbing technique for safe dissection of pituitary tumors.

Pituitary·2026

Same journal

Postoperative changes in circulating brain injury biomarkers in relation to long-term fatigue and cognitive outcomes after surgery for nonfunctioning pituitary adenomas.

Pituitary·2026

Same journal

Pituitary metastasis as an endocrine-neuro-ophthalmologic emergency: clinical red flags and outcomes from a contemporary tertiary-center series.

Pituitary·2026

Same journal

GH responsiveness to corticotropin-releasing hormone identifies corticotroph-like somatotroph adenomas in acromegaly.

Pituitary·2026

Same journal

Etomidate in severe hypercortisolism: early cortisol kinetics and clinical outcomes in a real-world cohort.

Pituitary·2026

Same journal

The effect of hypoprolactinemia on cardiometabolic effects of rosuvastatin in men: A matched Cohort Pilot Study.

Pituitary·2026

See all related articles

Search research articles

Related Experiment Video

Updated: May 20, 2026

Role of Diffusion MRI Tractography in Endoscopic Endonasal Skull Base Surgery

Role of Diffusion MRI Tractography in Endoscopic Endonasal Skull Base Surgery

Published on: July 5, 2021

Surgery for craniopharyngioma.

Michael Buchfelder¹, Sven-Martin Schlaffer, Fuhua Lin

¹Department of Neurosurgery, University of Erlangen-Nürnberg, Schwabachanlage 6, 91054, Erlangen, Germany. michael.buchfelder@uk-erlangen.de

|July 28, 2012

Summary

This summary is machine-generated.

Craniopharyngiomas, rare sellar tumors, present surgical challenges. Less aggressive resection combined with radiation may offer better outcomes than gross total resection due to lower surgical risks.

More Related Videos

Endoscopic Endonasal Trans-sphenoidal Approach: Minimally Invasive Surgery for Pituitary Adenomas

Endoscopic Endonasal Trans-sphenoidal Approach: Minimally Invasive Surgery for Pituitary Adenomas

Published on: January 17, 2018

A Craniotomy Surgery Procedure for Chronic Brain Imaging

A Craniotomy Surgery Procedure for Chronic Brain Imaging

Published on: February 15, 2008

Related Experiment Videos

Last Updated: May 20, 2026

Role of Diffusion MRI Tractography in Endoscopic Endonasal Skull Base Surgery

Role of Diffusion MRI Tractography in Endoscopic Endonasal Skull Base Surgery

Published on: July 5, 2021

Endoscopic Endonasal Trans-sphenoidal Approach: Minimally Invasive Surgery for Pituitary Adenomas

Endoscopic Endonasal Trans-sphenoidal Approach: Minimally Invasive Surgery for Pituitary Adenomas

Published on: January 17, 2018

A Craniotomy Surgery Procedure for Chronic Brain Imaging

A Craniotomy Surgery Procedure for Chronic Brain Imaging

Published on: February 15, 2008

Area of Science:

Neurosurgery
Pediatric Oncology
Endocrinology

Background:

Craniopharyngiomas are rare, benign tumors in the sellar region.
Diagnosis often occurs in childhood or adolescence.
Tumors can cause visual pathway compression, pituitary/hypothalamic dysfunction, or obstructive hydrocephalus.

Purpose of the Study:

To review surgical techniques and outcomes for craniopharyngiomas.
To focus on the morbidity and mortality associated with surgical interventions.
To compare different surgical philosophies in managing these tumors.

Main Methods:

Review of surgical techniques for craniopharyngioma resection.
Analysis of outcomes, including morbidity and mortality.
Discussion of gross total resection versus subtotal resection with adjuvant therapy.

Main Results:

Gross total resection offers cure but carries substantial surgical risks.
Less aggressive approaches (subtotal resection, cyst drainage) followed by irradiation may improve patient outcomes.
Radiation therapy variants are available for tumor progression control.

Conclusions:

Surgical management of craniopharyngiomas requires balancing tumor control with symptom aggravation.
Less aggressive surgical strategies combined with modern radiation techniques may be more beneficial than aggressive resection.
Careful consideration of surgical risks, morbidity, and mortality is crucial in treatment planning.