Sliding mode control of outbreaks of emerging infectious diseases

Yanni Xiao1, Xiaxia Xu, Sanyi Tang

  • 1Department of Applied Mathematics, Xi'an Jiaotong University, PR China.

Insights

This study introduces a mathematical model for infectious disease management using a threshold policy. The findings show that strategic control interventions can prevent outbreaks or maintain disease levels effectively.

Area of Science:

  • Mathematical Biology
  • Epidemiology
  • Control Theory

Background:

  • Classic epidemic models often lack dynamic control strategies.
  • Implementing control measures based on infection thresholds is crucial for disease management.

Purpose of the Study:

  • To propose and analyze a mathematical model for infectious disease systems incorporating a piecewise control function based on a threshold policy.
  • To investigate the long-term dynamics and stability of the proposed non-smooth system.

Main Methods:

  • Development of a piecewise mathematical model for infectious disease dynamics.
  • Analysis of the system's long-term behavior, including sliding motion on the switching surface.
  • Investigation of endemic states and sliding equilibrium.

Main Results:

  • The model exhibits sliding motion, representing rapid switching between control and no control.
  • Model solutions converge to endemic states or a sliding equilibrium depending on the threshold level.
  • The study demonstrates that threshold-based policies can effectively manage disease spread.

Conclusions:

  • A threshold policy with appropriate control intensity and density can prevent disease outbreaks.
  • This strategy allows for maintaining the number of infected individuals at a predetermined level.
  • The findings offer valuable insights for designing effective public health interventions.

Related Concept Videos

Steps in Outbreak Investigation01:18

Steps in Outbreak Investigation

In the ever-evolving field of public health, statistical analysis serves as a cornerstone for understanding and managing disease outbreaks. By leveraging various statistical tools, health professionals can predict potential outbreaks, analyze ongoing situations, and devise effective responses to mitigate impact. For that to happen, there are a few possible stages of the analysis:
Infectious Diseases and Their Occurrence01:28

Infectious Diseases and Their Occurrence

Infectious diseases appear in populations through various transmission patterns, influenced by pathogen characteristics, population immunity, environmental conditions, and social behavior. Understanding these patterns is essential for effective public health surveillance and intervention. These categories—sporadic, outbreak, epidemic, pandemic, and endemic—help frame the nature and scope of disease events.Sporadic diseases occur irregularly and infrequently, without a predictable temporal or...
Investigation of Disease Outbreaks01:23

Investigation of Disease Outbreaks

Multistate foodborne outbreaks pose significant public health risks and require meticulous investigation to identify sources and implement control measures. The Centers for Disease Control and Prevention (CDC) utilizes a dynamic seven-step process for these investigations, integrating data from laboratories, interviews, and environmental assessments to protect public health.Outbreak Detection: The detection of multistate outbreaks typically begins with PulseNet, the CDC's national laboratory...
Principles of Disease Surveillance01:26

Principles of Disease Surveillance

Disease surveillance is the systematic collection, analysis, and interpretation of health data essential to the planning, implementation, and evaluation of public health practice. This process integrates data dissemination to entities responsible for preventing and controlling disease, injury, and disability. Surveillance systems provide crucial information for action, helping public health authorities make informed decisions to manage and prevent outbreaks, ensure public safety, optimize...
Infection01:20

Infection

When a pathogen enters the body and reproduces, it can cause an infection, damage body cells, and cause illness symptoms that eventually lead to disease. Therefore, its prevention requires breaking the chain of infection.
The chain begins with pathogens: bacteria, viruses, fungi, prions, or parasites such as protozoa helminths. These can be present on the skin as transient or resident flora, or they can be acquired from the environment. Identifying and treating the type of infection and...
Causality in Epidemiology01:21

Causality in Epidemiology

Causality or causation is a fundamental concept in epidemiology, vital for understanding the relationships between various factors and health outcomes. Despite its importance, there's no single, universally accepted definition of causality within the discipline. Drawing from a systematic review, causality in epidemiology encompasses several definitions, including production, necessary and sufficient, sufficient-component, counterfactual, and probabilistic models. Each has its strengths and...