In-transit metastases from squamous cell carcinoma penis

Area of Science:

• Oncology
• Surgical Pathology
• Medical Oncology

Background:

• In-transit metastasis is defined as tumor spread to lymphatic channels between the primary tumor and regional lymph nodes.
• Penile squamous cell carcinoma can metastasize to regional lymph nodes.
• Cutaneous metastases can occur in various cancers, but in-transit presentation is less common.

Purpose of the Study:

• To report an uncommon case of in-transit penile cancer metastasis.
• To discuss the clinical presentation and implications of this rare metastatic pattern.

Main Methods:

• Case report of a 65-year-old male patient.
• Review of patient's medical history including partial penile amputation and lymph node resection.
• Clinical examination and documentation of metastatic lesions.

Main Results:

• The patient presented with multiple cutaneous metastatic lesions in the pubic region and scrotum.
• These lesions were located between the primary tumor site and the resected lymph node basin.
• This presentation is consistent with in-transit metastases.

Conclusions:

• In-transit metastases represent a distinct pattern of cancer spread.
• This case underscores the variability in penile cancer metastasis.
• Awareness of such uncommon presentations is crucial for accurate diagnosis and management.