[Smell reception and neurogenesis in the olfactory epithelium]

Experimental anosmia induced by 1% ZnSO4 solution triggered some structural and functional changes in olfactory epithelium of strain C57BL/6 mice. It was stimulated by various odors: isoamyl acetate, butyl acetate and some substances present in mice urine. It was registered that the rate of physiological responses recovery differed for various odors, being the higher in case of isoamyl acetate and butyl acetate treatment and slower with odors of the biological origin. The study of spatial distribution of the responses evoked by the odors of various quality has demonstrated that the areas of the most rapid recovery corresponded to the same areas of the epithelium of intact mice where higher responses for these stimuli were registered.