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Updated: May 20, 2026

Modeling Multiple Sclerosis in the Two Sexes: MOG35-55-Induced Experimental Autoimmune Encephalomyelitis
Published on: October 13, 2023
Pregnancy and multiple sclerosis
1Department of Neurology, Stony Brook MS Comprehensive Care Center, Stony Brook University, Stony Brook, NY 11794-8121, USA. patricia.coyle@stonybrookmedicine.edu
Abstract:
Pregnancy is a major concern in multiple sclerosis (MS), because the typical patient is a young woman of childbearing age. This article reviews the impact of pregnancy on MS. Disease activity decreases, particularly during the last trimester. There is a temporary rebound of disease activity in the 3 months postpartum. Pregnancy and the postpartum period have many implications for counseling and for therapeutic decision making in MS.
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