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[Relevance of diabetes in high cardiovascular risk hypertensive patients]

Julián Segura1, Alejandro de la Sierra, Sandra Fernández

  • 1Unidad de Hipertensión Arterial, Servicio de Nefrología, Hospital Universitario 12 de Octubre, Madrid, España.

Medicina Clinica
|July 31, 2012
PubMed

Insights

Hypertensive patients with type 2 diabetes experience higher rates of target organ damage and cardiovascular disease compared to those without diabetes but with multiple risk factors. Diabetes significantly increases cardiovascular risk in hypertensive individuals.

Area of Science:

  • Cardiology
  • Endocrinology
  • Nephrology

Context:

  • Hypertension is a major cardiovascular risk factor.
  • Type 2 diabetes mellitus exacerbates cardiovascular risk.
  • Identifying target organ damage (TOD) and established cardiovascular disease (CVD) is crucial for risk stratification.

Purpose:

  • To compare the prevalence of TOD and CVD in hypertensive patients with type 2 diabetes versus those without diabetes but with at least three cardiovascular risk factors (CVRF).

Summary:

  • This cross-sectional study analyzed 4,725 hypertensive patients, comparing a group with type 2 diabetes (N=2,608) against a non-diabetic group with ≥3 CVRF (N=2,117).
  • Prevalence of TOD (left ventricular hypertrophy, microalbuminuria, renal failure) and CVD was assessed.
  • Hypertensive patients with type 2 diabetes exhibited higher rates of obesity, TOD, and CVD, with diabetes independently associated with increased risk.

Impact:

  • Hypertensive patients with type 2 diabetes face a greater burden of TOD and CVD.
  • These findings highlight the intensified cardiovascular risk in hypertensive individuals with diabetes.
  • This underscores the need for proactive cardiovascular risk management in this patient population.
Abstract

Keywords:
Cardiovascular riskChronic renal diseaseDiabetesEnfermedad renal crónicaHipertensiónHypertensionLesión de órgano dianaRiesgo cardiovascularTarget organ disease

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