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Published on: January 28, 2019

Characteristics of rotavirus gastroenteritis in hospitalized children in Pune

Ashwin Borade1, Ajit Singh Bais, Vaijayanti Bapat

  • 1Department of Pediatrics, Sant Dnyaneshwar Medical Education and Research, Pune, Maharashtra, India. ashwinborade@yahoomail.com

Indian Journal of Medical Sciences
|July 31, 2012
PubMed

Insights

Rotavirus remains a significant cause of infantile diarrhea, even with good hygiene and vaccination. This study found rotavirus infection in 35.77% of young children hospitalized for acute gastroenteritis, with peak incidence in winter.

Area of Science:

  • Pediatrics
  • Infectious Diseases
  • Gastroenterology

Background:

  • Diarrheal diseases significantly impact children globally, particularly in developing nations.
  • Rotavirus is a major contributor to the etiology of diarrheal diseases worldwide.
  • Despite advancements in hygiene and vaccination, rotavirus continues to be a prevalent pathogen.

Purpose of the Study:

  • To investigate the demographic, clinical, and laboratory characteristics of rotavirus infections in children under five years old.
  • To identify associated symptoms and potential extraintestinal manifestations of rotavirus in hospitalized pediatric patients.

Main Methods:

  • A prospective study was conducted from June 2009 to June 2011.
  • Included were 246 hospitalized children under five diagnosed with acute gastroenteritis.
  • Data analysis involved the chi-square test and SPSS version 17.0.

Main Results:

  • Rotavirus infection was confirmed in 35.77% (88/246) of the study population.
  • The highest incidence occurred in infants aged 11-20 months (38.63%).
  • Associated symptoms included fever (48.86%), vomiting (29.54%), and abdominal pain (53.4%).
  • A winter peak incidence was observed, with 5.68% of stool-positive cases also showing rotavirus in urine, suggesting extraintestinal spread.

Conclusions:

  • Rotavirus is a critical cause of infantile diarrhea in urban settings like Pune, irrespective of hygiene and vaccination status.
  • Fever, vomiting, and abdominal pain are significantly associated with rotavirus infection.
  • The study observed a peak incidence in December and January and noted a correlation between stool and blood positivity for rotavirus.
Abstract

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