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Rous Sarcoma Virus (RSV) and Cancer

Rous Sarcoma Virus (RSV) and Cancer

Rous Sarcoma virus or RSV was discovered by F. Peyton Rous in the year 1911 as a filterable transmissible agent that could cause tumors in chickens. He won a Nobel Prize for this discovery in 1966. His experiments clearly demonstrated that some cancers could be caused by infectious agents and led to the discovery of many more cancer-causing viruses in animals as well as humans.
RSV is a retrovirus that contains two copies of a plus-strand RNA genome. Its genome consists of four main open...

Rous Sarcoma Virus (RSV) and Cancer

Rous Sarcoma Virus (RSV) and Cancer

Rous Sarcoma virus or RSV was discovered by F. Peyton Rous in the year 1911 as a filterable transmissible agent that could cause tumors in chickens. He won a Nobel Prize for this discovery in 1966. His experiments clearly demonstrated that some cancers could be caused by infectious agents and led to the discovery of many more cancer-causing viruses in animals as well as humans.
RSV is a retrovirus that contains two copies of a plus-strand RNA genome. Its genome consists of four main open...

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Related Experiment Video

Updated: May 20, 2026

Establishment of Cancer Stem Cell Cultures from Human Conventional Osteosarcoma

Establishment of Cancer Stem Cell Cultures from Human Conventional Osteosarcoma

Published on: October 14, 2016

Pediatric oral leiomyosarcoma: rare case report.

C V Divyambika¹, S Sathasivasubramanian, C L Krithika

¹Department of Oral Medicine and Radiology, Sri Ramachandra University, Porur, Chennai - 600118, India. divyambika@rediffmail.com

Journal of Cancer Research and Therapeutics

|July 31, 2012

Summary

This case report details a rare oral leiomyosarcoma in an eight-year-old child. Prompt recognition and multimodality treatment are crucial for this unusual pediatric soft tissue sarcoma.

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Last Updated: May 20, 2026

Establishment of Cancer Stem Cell Cultures from Human Conventional Osteosarcoma

Establishment of Cancer Stem Cell Cultures from Human Conventional Osteosarcoma

Published on: October 14, 2016

Area of Science:

Oncology
Pediatric Pathology
Surgical Oncology

Background:

Soft tissue sarcomas are diverse malignant neoplasms originating from mesenchymal cells.
Leiomyosarcomas specifically display smooth muscle differentiation.
Oral leiomyosarcomas are exceptionally rare, particularly in pediatric patients.

Observation:

This report focuses on an eight-year-old child diagnosed with oral leiomyosarcoma.
The tumor's presentation in the oral cavity of a child is highly unusual.
This highlights the rarity of primary oral leiomyosarcoma in this age group.

Findings:

The case underscores the infrequent occurrence of oral leiomyosarcoma in children.
Early identification of this rare tumor is critical for effective management.
Multimodality treatment approaches are emphasized for optimal outcomes.

Implications:

This case emphasizes the importance of considering rare diagnoses in pediatric oncology.
Prompt recognition of oral leiomyosarcoma can lead to timely intervention.
Effective management strategies for rare pediatric soft tissue sarcomas require further investigation.