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Prostate Metastasis in Oral Malignant Melanoma - A Case Report
Vaishnavi Muthukumaran1, S Aravind Warrier1, Barath Balaji2
1Department of Oral Medicine and Radiology, Sri Ramachandra Dental College and Hospital, Sri Ramachandra Institute of Higher Education and Research (Deemed to be University), Chennai, Tamil Nadu, India.
Summary
This case report details a rare instance of oral malignant melanoma with distant metastasis to the prostate gland. This highlights the unusual spread patterns of melanoma, impacting prognosis and treatment strategies.
Area of Science:
- Oncology
- Pathology
Background:
- Melanoma is a significant cause of cancer mortality, particularly when metastatic.
- Metastasis is the primary driver of melanoma-related deaths, with a poor 5-year survival rate (<30%) for distant metastatic cases.
Observation:
- A case of oral malignant melanoma in an elderly male patient is presented.
- The patient had a primary tumor on the maxillary gingiva with distant metastases to the liver and prostate.
Findings:
- Metastasis to the liver is a known occurrence in malignant melanoma.
- Metastasis to the prostate gland from oral malignant melanoma is exceptionally rare and noteworthy.
Implications:
- This case underscores the unpredictable metastatic potential of melanoma.
- Understanding rare metastatic patterns is crucial for accurate diagnosis, prognosis, and developing targeted therapies for advanced melanoma.

