Pasteurella (Mannheimia) haemolytica septicemia in an infant: a case report

Warunee Punpanich1, Sarunya Srijuntongsiri

  • 1Queen Sirikit National Institute of Child Health, College of Medicine, Rangsit University, Bangkok, Thailand. waruneep@gmail.com

Insights

Septicemia caused by Mannheimia haemolytica is rare. This report details a fatal case in an infant with prolonged fever, sepsis, and pneumonitis, highlighting unusual systemic infections.

Area of Science:

  • Veterinary Medicine
  • Human Medicine
  • Infectious Diseases

Background:

  • Septicemia, a bloodstream infection, is typically caused by common bacteria.
  • Mannheimia haemolytica is primarily known as a cause of respiratory disease in animals.
  • Systemic infections in humans, especially infants, are infrequently associated with this pathogen.

Observation:

  • A seven-month-old infant presented with persistent fever, sepsis, and pneumonitis.
  • No history of animal bites or known contact with animals was reported.
  • The infant's condition was ultimately fatal, diagnosed as M. haemolytica septicemia.

Findings:

  • This case represents a rare instance of fatal septicemia caused by Mannheimia haemolytica in a human infant.
  • The absence of typical risk factors (animal contact) makes this case particularly noteworthy.
  • A review of rare systemic Mannheimia infections is provided.

Implications:

  • Clinicians should consider rare pathogens like M. haemolytica in severe pediatric infections, even without clear exposure history.
  • This case underscores the potential for zoonotic transmission of animal pathogens.
  • Further research into the epidemiology and transmission of M. haemolytica in humans is warranted.

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