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Related Concept Videos

Disorders of the Female Reproductive System01:24

Disorders of the Female Reproductive System

The female reproductive system can be affected by several disorders, including Premenstrual Syndrome (PMS), Premenstrual Dysphoric Disorder (PMDD), endometriosis, and various forms of cancer. PMS and PMDD are cyclical conditions that cause physical and emotional distress, with symptoms that include edema, mood swings, and food cravings. PMDD is a more severe form of PMS characterized by increased symptom severity that peaks during the luteal phase and tends to improve or resolve shortly after...
Menses Phase01:18

Menses Phase

The uterine cycle begins with the menstrual phase, which is considered day one of the cycle and typically lasts about five days. This phase is characterized by the degeneration and shedding of the stratum functionalis, the functional layer of the endometrium.
When fertilization does not occur, the corpus luteum deteriorates, causing a significant drop in the levels of estrogen and progesterone in the body. This hormonal decrease triggers the release of prostaglandins, which cause the uterine...
Hormonal Regulation of the Menstrual Cycle01:22

Hormonal Regulation of the Menstrual Cycle

The ovarian cycle regulates endometrial changes throughout a single menstrual cycle via the coordinated action of gonadotrophin-releasing hormone (GnRH) and gonadotrophins.
At puberty, GnRH begins a pulsatile release pattern, which triggers the anterior pituitary gland to secrete follicle-stimulating hormone (FSH) and luteinizing hormone (LH). The frequency and amplitude of GnRH pulses vary across the menstrual cycle, with faster pulses favoring LH release and slower pulses favoring FSH release.
Disorders of the Male Reproductive System01:20

Disorders of the Male Reproductive System

Men's health issues are increasingly recognized as significant, with several conditions posing common threats. Among these, testicular cancer is especially prevalent in younger men, particularly those aged 20 to 35 years. The disease often manifests as a painless mass in the testicles, sometimes accompanied by a sensation of heaviness or a dull ache.
Prostate disorders are another major concern. These conditions can impair urinary flow due to the prostate's location around the urethra. Symptoms...
The Menstrual Cycle01:19

The Menstrual Cycle

The menstrual cycle is a recurrent sequence of changes in the uterine endometrium, specifically its functional layer, the stratum functionalis. This cycle prepares the uterus for potential pregnancy. This cycle typically spans 21–35 days, averaging 28 days, and aligns with the ovarian cycle, regulated by fluctuating levels of ovarian hormones, primarily estrogen and progesterone.
The menstrual phase occurs from days 1 to 5 and involves the shedding of the stratum functionalis, as a uterine...
Depressive Disorders: MDD and Dysthymia01:27

Depressive Disorders: MDD and Dysthymia

Depressive disorders are a group of mental health conditions characterized by pervasive feelings of sadness, diminished pleasure in life, and a significant impact on daily functioning. These conditions are most prevalent in individuals during their 30s and affect women at twice the rate of men. Contrary to popular belief, younger individuals are generally more susceptible to these disorders than older adults. Two key types of depressive disorders include Major Depressive Disorder (MDD) and...

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Related Experiment Video

Updated: May 20, 2026

Herbs-Partitioned Moxibustion on the Navel in a Rat Model of Primary Dysmenorrhea with Cold Coagulation and Blood Stasis
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Herbs-Partitioned Moxibustion on the Navel in a Rat Model of Primary Dysmenorrhea with Cold Coagulation and Blood Stasis

Published on: October 4, 2024

Menstrual disorders.

Efthimios Deligeoroglou, George Creatsas

    Endocrine Development
    |August 1, 2012
    PubMed
    Summary
    This summary is machine-generated.

    Adolescent menstrual disorders like amenorrhea and abnormal uterine bleeding are common due to immature hypothalamic-pituitary-ovarian (HPO) axis function. Early evaluation and management are crucial for reproductive health.

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    Herbs-Partitioned Moxibustion on the Navel in a Rat Model of Primary Dysmenorrhea with Cold Coagulation and Blood Stasis
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    Analysis of Raw and Processed Cyperi Rhizoma Samples Using Liquid Chromatography-Tandem Mass Spectrometry in Rats with Primary Dysmenorrhea
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    Analysis of Raw and Processed Cyperi Rhizoma Samples Using Liquid Chromatography-Tandem Mass Spectrometry in Rats with Primary Dysmenorrhea

    Published on: December 23, 2022

    Area of Science:

    • Gynecology
    • Adolescent Medicine
    • Reproductive Endocrinology

    Background:

    • Menstrual disorders are prevalent in adolescence, causing significant patient and parental stress.
    • Variations in menstrual cycles are common, primarily due to the immature hypothalamic-pituitary-ovarian (HPO) axis.

    Purpose of the Study:

    • To outline a stepwise and logical evaluation approach for common adolescent menstrual disorders.
    • To emphasize the importance of early and appropriate management to prevent future reproductive complications.

    Main Methods:

    • Review of conditions including primary/secondary amenorrhea, abnormal uterine bleeding, and dysmenorrhea.
    • Diagnostic criteria for dysfunctional uterine bleeding, emphasizing exclusion of organic causes.
    • Differentiation between primary and secondary dysmenorrhea based on pelvic pathology.

    Main Results:

    • Amenorrhea is defined as the failure to achieve menarche (primary) or cessation of menses (secondary).
    • Abnormal uterine bleeding requires ruling out organic causes before diagnosing dysfunctional uterine bleeding.
    • Dysmenorrhea, painful menstruation, is the most frequent gynecological complaint in young girls.

    Conclusions:

    • Adolescent menstrual disorders necessitate careful, stepwise evaluation.
    • Timely intervention is essential to safeguard future reproductive potential.
    • Understanding the HPO axis immaturity is key to managing these conditions.