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Updated: May 20, 2026

Imaging Features of Systemic Sclerosis-Associated Interstitial Lung Disease
Published on: June 16, 2020
Interstitial Pneumonia associated with ulcerative colitis: high-resolution computed tomography and pathologic
Naoko Ikehara1, Kiminori Fujimoto, Junko Sadohara
1Department of Radiology, Kurume University School of Medicine, 67 Asahi-machi, Kurume, 830-0011, Japan.
Ulcerative colitis (UC) can cause lung issues like interstitial pneumonia. This case highlights a patient with UC who developed nonspecific interstitial pneumonia, emphasizing the need for careful evaluation of pulmonary symptoms in UC patients.
Area of Science:
- Pulmonary Medicine
- Gastroenterology
- Pathology
Background:
- Ulcerative colitis (UC) is a chronic inflammatory bowel disease with known extraintestinal manifestations.
- Pulmonary involvement in UC, though less common, can present as various conditions including interstitial pneumonia.
Observation:
- A 61-year-old nonsmoking woman with a history of UC presented with pulmonary symptoms.
- High-resolution computed tomography (HRCT) revealed multifocal consolidation and ground-glass opacities in the peripheral lung parenchyma.
- Lung biopsy confirmed a pattern consistent with cellular and fibrotic nonspecific interstitial pneumonia.
Findings:
- The patient's pulmonary findings were pathologically consistent with nonspecific interstitial pneumonia.
- The clinical course suggested a possible association between UC and the observed interstitial pneumonia.
Implications:
- This case underscores the importance of considering pulmonary complications in patients with ulcerative colitis.
- Prompt diagnosis and management of lung disease in UC patients may improve patient outcomes.
- Further research into the mechanisms linking UC and interstitial lung disease is warranted.
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