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Antibiotic resistance is a major public health concern that arises when bacteria evolve mechanisms to withstand the effects of antibiotic treatments. This resistance can be intrinsic, acquired through genetic mutations, or transferred between bacteria via horizontal gene transfer. The development of antibiotic resistance poses significant challenges in treating bacterial infections and necessitates ongoing research to develop new therapeutic strategies.Intrinsic resistance occurs when bacterial...

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Updated: May 20, 2026

Isolation and Identification of Waterborne Antibiotic-Resistant Bacteria and Molecular Characterization of their Antibiotic Resistance Genes

Isolation and Identification of Waterborne Antibiotic-Resistant Bacteria and Molecular Characterization of their Antibiotic Resistance Genes

Published on: March 3, 2023

Antimicrobial resistance: a complex issue.

J F Acar¹, G Moulin

¹La Haute Marche, B.P. 90203, 35302 Fougères, France.

Revue Scientifique Et Technique (International Office of Epizootics)

|August 2, 2012

Summary

This summary is machine-generated.

Antimicrobial resistance, a natural bacterial survival mechanism, is a growing public health concern. Reducing antibiotic use is key, but comprehensive strategies are needed to combat resistant bacteria.

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Isolation and Identification of Waterborne Antibiotic-Resistant Bacteria and Molecular Characterization of their Antibiotic Resistance Genes

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Published on: March 3, 2023

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Published on: July 24, 2021

Area of Science:

Microbiology
Public Health
Infectious Diseases

Background:

Antibiotic discovery revolutionized medicine, but antibiotic resistance emerged by the late 1950s.
Multidrug-resistant bacteria pose significant threats to both human and animal health globally.
Antimicrobial resistance is an intrinsic bacterial trait, predating human antibiotic use, facilitating survival and adaptation.

Purpose of the Study:

To highlight the complex nature of antimicrobial resistance.
To explain the mechanisms of resistance gene transfer.
To emphasize the role of antibiotics as selectors for resistance.

Main Methods:

Review of existing literature on antimicrobial resistance.
Analysis of bacterial adaptation and resistance mechanisms.
Examination of horizontal gene transfer processes (conjugation, transduction, transformation).

Main Results:

Antimicrobial resistance is a natural bacterial survival strategy.
Resistance genes transfer horizontally between bacteria.
Antibiotics act as potent selective agents driving antimicrobial resistance.

Conclusions:

Antimicrobial resistance is a complex, multifaceted issue requiring a comprehensive approach.
Reducing antimicrobial drug use is a critical component of control strategies.
Integrated measures are essential to effectively manage and mitigate antimicrobial resistance.