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Updated: May 20, 2026

Chemoselective Preparation of 1-Iodoalkynes, 1,2-Diiodoalkenes, and 1,1,2-Triiodoalkenes Based on the Oxidative Iodination of Terminal Alkynes
09:54

Chemoselective Preparation of 1-Iodoalkynes, 1,2-Diiodoalkenes, and 1,1,2-Triiodoalkenes Based on the Oxidative Iodination of Terminal Alkynes

Published on: September 12, 2018

An iodocyclization approach to substituted 3-iodothiophenes

Bartolo Gabriele1, Raffaella Mancuso, Giuseppe Salerno

  • 1Dipartimento di Scienze Farmaceutiche, Università della Calabria, 87036 Arcavacata di Rende (CS), Italy. b.gabriele@unical.it

The Journal of Organic Chemistry
|August 2, 2012
PubMed
Summary

Researchers developed a new method for synthesizing 3-iodothiophenes using direct iodocyclization of alkynylthiol compounds. This efficient process converts readily available precursors into valuable thiophene derivatives in good yields.

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