Reliability and validity of the acanthosis nigricans screening tool for use in elementary school-age children by

Leslie K Scott1, Lynne M Hall

  • 1College of Nursing, University of Kentucky, Lexington, KY, USA. lkscot0@uky.edu

Insights

This study validated an acanthosis nigricans (AN) screening tool for children. The tool accurately and reliably identified AN in diverse elementary school students.

Area of Science:

  • Pediatric Endocrinology
  • Dermatology
  • Public Health Screening

Background:

  • Acanthosis nigricans (AN) is a skin condition often associated with insulin resistance and obesity.
  • Early identification of AN in children is crucial for timely intervention and management of associated metabolic conditions.
  • A reliable screening tool is needed for diverse pediatric populations.

Purpose of the Study:

  • To evaluate the reliability and validity of a specific acanthosis nigricans (AN) screening tool.
  • To assess the tool's effectiveness across various ethnic groups in elementary school-aged children.
  • To determine the tool's ease of use and reproducibility among clinicians.

Main Methods:

  • Cross-sectional observational study involving 288 children aged 5-12 years.
  • Three nurse clinicians independently assessed children using a 0-4 grade AN screening tool.
  • Inter-rater reliability was assessed using the kappa statistic.

Main Results:

  • The AN screening tool demonstrated consistent and appropriate identification of AN across different ethnic groups.
  • Clinicians achieved high agreement, with 98% concordance within one grade.
  • Substantial inter-rater agreement was confirmed (kappa = .822, p ≤ .001).
  • Grade four AN was detected consistently, irrespective of child's sex, BMI, or ethnicity.

Conclusions:

  • The acanthosis nigricans (AN) screening tool is reliable and valid for use in diverse elementary school-aged children.
  • The tool is user-friendly and reproducible, facilitating effective screening in pediatric populations.
  • This validated tool can aid in early detection and management of AN and related metabolic concerns.