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Assessment and Evaluation of the High Risk Neonate: The NICU Network Neurobehavioral Scale
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[Perinatal pathology and risk groups in postnatal ontogeny]

A F Iakovtsova, V D Markovskiĭ, V S Vasiuta

    Arkhiv Patologii
    |January 1, 1990
    PubMed

    Insights

    Perinatal pathology can lead to adult diseases. Early fetal development issues in the cardiovascular system, immune system, and endocrine glands may cause later health problems like atherosclerosis and hormonal imbalances.

    Area of Science:

    • Perinatology
    • Developmental Biology
    • Pathology

    Background:

    • Perinatal pathologies are increasingly recognized as significant contributors to long-term health issues.
    • Understanding the fetal origins of adult disease is crucial for preventative medicine.

    Purpose of the Study:

    • To investigate the link between perinatal pathologies and subsequent diseases in children and adults.
    • To identify specific fetal organs and systems affected by maternal conditions like toxicosis and hypertension.

    Main Methods:

    • Examination of the fetal cardiovascular system and placental vessels.
    • Analysis of the immunological system and sex glands in large fetuses.
    • Assessment of the thyroid and sex glands in newborns.

    Main Results:

    • Pathological development was observed in the cardiovascular system, placental vessels, immune system, and endocrine glands during pregnancy.
    • These fetal developmental issues are associated with conditions such as early atherosclerosis, myocardiopathy, and sexual disturbances.

    Conclusions:

    • Perinatal pathologies represent a critical "prepathological" stage for various adult diseases.
    • Early identification and intervention in fetal development can potentially mitigate risks for conditions like endocrinopathy and immunodeficient states.

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