Vitamin D and depression: is there a relationship in young women?

Depression is emerging as a leading cause of morbidity and mortality in young adults. New biological assessment strategies such as biological markers are needed to more accurately assess for depression in this age group. Vitamin D may present such an opportunity.

A descriptive correlational design with convenience sampling was used to address the research question: Is there a relationship between vitamin D serum levels and depression scores in young adult women?

One hundred thirty-nine participants completed a health questionnaire, Beck Depression Inventory, and had serum vitamin D, 25(OH)D, levels drawn.

No statistically significant correlation between vitamin D level and depression was identified. Statistically significant differences between African American and Caucasian women were detected on vitamin D levels but not on the Beck Depression Inventory.

Based on the results of this study, vitamin D cannot be used as a biomarker for depression in women aged 18 to 24 years. Clinical implications of no relationship between vitamin D and depression will be explored and the cut-point for serum 25(OH)D levels will be discussed.