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Genetic Overlap between Holoprosencephaly and Kallmann Syndrome.

K Vaaralahti1, T Raivio, R Koivu

  • 1Institute of Biomedicine/Physiology, University of Helsinki, Finland.

Molecular Syndromology
|August 3, 2012
PubMed
Summary

Genetic overlap exists between Kallmann syndrome (KS) and holoprosencephaly (HPE). This study identified novel SIX3 and GLI2 gene variants in KS patients, suggesting shared genetic underpinnings for these midline defect disorders.

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