Treatment of refractory orbital pseudotumors with pulsed chemotherapy
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G L Paris1, G F Waltuch, P R Egbert
1Department of Ophthalmology, Stanford University Medical Center, CA.
Ophthalmic Plastic and Reconstructive Surgery
|January 1, 1990
Abstract:
Five patients with orbital pseudotumor refractive to initial therapy are discussed. Three had a destructive granulomatous process associated with a sclerosing component. Two exhibited a predominantly lymphocytic infiltration. Chemotherapy with Prednisone (100 mg/day) and either Cytoxan (100 mg/day) or Chlorambucil (10 mg/day) in 5-day pulses is described. All patients responded clinically to this treatment without unfavorable side effects.