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Published on: February 9, 2011
[Acute otitis media: prevalence of ear pathogens in patients at a public hospital]
Patricia A Sommerfleck1, Patricia C Bernáldez, Claudia M Hernández
1Servicio de Otorrinolaringología, Hospital Nacional de Pediatría SAMIC Prof. Dr. Juan P. Garrahan, Ciudad Autónoma de Buenos Aires, Argentina. p.sommerfleck@gmail.com
Background And Objective:
Acute otitis media (AOM) is one of the most common diseases in childhood and is the most common cause of antibiotic prescriptions in children. The gold standard for identifying the pathogens causing AOM is tympanocentesis. This is only possible in the stage of AOM when exudate is retained in the middle ear. The aim of this study was to describe the prevalence of organisms causing AOM in eutrophic patients at a public paediatric hospital.
Material And Methods:
We included all patients with AOM diagnosed by otomicroscopy with purulent exudate retained in middle ear and suppurative AOM with inadequate drainage consulting at the Otorhinolaryngology Department in a paediatric tertiary care centre from 2 May 2009 to 31 August 2010.
Results:
There were 324 patients included in the study, with 180/324 (55.6%) being male. The median age was 8 months (interquartile range: 4 to 15 months). Bilateral AOM was recorded in 109/324 (33.6%) patients (433 samples for culture were obtained by tympanocentesis in 324 patients). At diagnosis, 37% (120/324) of the children had been receiving antimicrobial treatment. Of the patients who had received antibiotics, 71/120 (59.1%) had bacterial growth in middle ear fluid (MEF) cultures, with 51/71 (71.8%) being susceptible to the antibiotic they received; 20/71 (28.2%) patients were receiving an antibiotic that did not cover the spectrum of organisms isolated.
Conclusion:
The pathogens most frequently isolated are Streptococcus pneumoniae (39.5%), Haemophilus influenzae (37.4%), Moraxella catarrhalis (6.1%) and Streptococcus pyogenes (3.0%).
Insights
This study identified the most common bacteria causing acute otitis media (AOM) in children. Streptococcus pneumoniae and Haemophilus influenzae were the most prevalent pathogens, informing antibiotic treatment strategies for AOM.
Area of Science:
- Pediatric Infectious Diseases
- Microbiology
- Otolaryngology
Context:
- Acute otitis media (AOM) is a frequent childhood illness and a leading reason for pediatric antibiotic prescriptions.
- Tympanocentesis is the standard for identifying AOM pathogens but requires middle ear exudate.
Purpose:
- To determine the prevalence of microorganisms responsible for AOM in pediatric patients at a public hospital.
Summary:
- A study of 324 children with AOM found Streptococcus pneumoniae (39.5%) and Haemophilus influenzae (37.4%) as the most common pathogens.
- Nearly 40% of children had received prior antibiotic treatment, with some receiving ineffective antibiotic regimens.
- Middle ear fluid cultures identified bacterial growth in 59.1% of children who had received antibiotics.
Impact:
- Findings aid in optimizing antibiotic selection for AOM, potentially reducing treatment failures and antimicrobial resistance.
- Highlights the need for accurate pathogen identification in pediatric AOM management.
- Provides epidemiological data on AOM-causing organisms in a specific pediatric population.
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