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Updated: May 19, 2026

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An In Vitro Assay to Detect tRNA-Isopentenyl Transferase Activity
Published on: October 8, 2018
Homeostatic mechanisms by alternative forms of tRNA synthetases
1Department of Cancer Biology, Scripps Florida, 130 Scripps Way, Jupiter, FL 33458, USA.
Trends in Biochemical Sciences
|August 4, 2012
Abstract:
Although aminoacyl tRNA synthetases (aaRSs) act in translation, numerous examples demonstrate ex-translational functions in fundamental networks of higher organisms. These functions involve modified versions of aaRSs and natural fragments. The interplay of aaRS-derived entities appears to be at the heart of homeostatic mechanisms controlling angiogenesis, inflammation, metabolism, and tumorigenesis.
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