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Viral Nanoparticles for In vivo Tumor Imaging
Published on: November 16, 2012
Photodynamic activity of viral nanoparticles conjugated with C60
Amy M Wen1, Mary J Ryan, Alice C Yang
1Department of Biomedical Engineering, Case Western Reserve University, 10900 Euclid Avenue, Cleveland, OH 44106, USA.
Chemical Communications (Cambridge, England)
|August 4, 2012
Abstract:
The development of viral nanoparticles (VNP) displaying multiple copies of the buckyball (C(60)) and their photodynamic activity is described. VNP-C(60) conjugates were assembled using click chemistry. Cell uptake and cell killing using white light therapy and a prostate cancer cell line is demonstrated.
