Related Experiment Video
Updated: May 19, 2026

Methods to Evaluate Cytotoxicity and Immunosuppression of Combustible Tobacco Product Preparations
Published on: January 10, 2015
Might cigarettes be a "smoking gun" to reduce taxane myelotoxicity?
Lionel D Lewis1, Mark J Ratain
1Department of Medicine, Dartmouth-Hitchcock Medical Center, Lebanon, NH, USA. lionel.lewis@dartmouth.edu
Abstract:
de Graan and colleagues report a retrospective study of the effects of cigarette smoking on taxane pharmacokinetics and myelosuppression. There was no difference in taxane pharmacokinetic clearance between smokers and nonsmokers. Further prospective studies of the effects of cigarette smoking on myelosuppression would be of interest.
Related Concept Videos
Drugs that Stabilize Microtubules
Chemotherapy-Induced Nausea and Vomiting: Cannabinoids
Two synthetic agonists of THC,...
Drugs that Destabilize Microtubules

