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Study on Chinese common allergens of contact dermatitis
Dermatosen in Beruf Und Umwelt. Occupation and Environment
|September 1, 1990
Summary
Patch testing identified common allergens in contact dermatitis, with nickel, fragrance mix, and p-phenylenediamine being most prevalent. Further testing revealed specific sensitizing agents in cases with initial negative results.
Area of Science:
- Dermatology
- Allergology
- Toxicology
Background:
- Contact dermatitis is a common skin condition.
- Accurate allergen identification is crucial for effective management.
- European Standard Allergens (ESA) are widely used for patch testing.
Purpose of the Study:
- To determine the prevalence of positive reactions to ESA in suspected contact dermatitis cases.
- To identify the most common allergens causing contact dermatitis.
- To investigate allergens in patients with negative ESA results.
Main Methods:
- Patch tests were conducted on 204 patients suspected of having contact dermatitis.
- Tests followed the European Standard Allergens (ESA) protocol.
- Additional patch tests were performed on a subset of patients with suspected individual agents.
Main Results:
- A positive reaction to ESA was observed in 58.33% of cases.
- The most frequent allergens were nickel (15.7%), fragrance mix (11.8%), and p-phenylenediamine (8.8%).
- In patients with negative ESA results, ampicillin and thiomersal were identified as common sensitizers.
Conclusions:
- ESA patch testing is effective in diagnosing contact dermatitis.
- Nickel, fragrance mix, and p-phenylenediamine are significant allergens.
- Individualized testing is valuable for identifying less common sensitizers.
