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Updated: May 19, 2026

Murine Hind Limb Long Bone Dissection and Bone Marrow Isolation
Published on: April 14, 2016
Fibro-osseous disease: harmonizing terminology with biology
Claudia E Noffke1, Erich J Raubenheimer, David MacDonald
1Division of Maxillofacial and Oral Radiology, Oral Health Centre, Medunsa Campus, University of Limpopo, Medunsa, Gauteng, 0204 South Africa. claudia.noffke@ul.ac.za
Abstract:
Classification systems and associated terminology are inherently slow in reflecting rapidly unfolding scientific discoveries in the mechanism and presentation of diseases. Misleading concepts, which often have historical value only, may become entrenched in the literature, leading to confusion and inaccurate communication. The purpose of this communication is to stimulate discussion and debate on inappropriate terminology associated with fibro-osseous disease that continues to be perpetuated in the literature. Use of the terms "cementum," "aggressive," "active," "gigantiform," and "maturation" are questioned, and the criteria applied to the interpretation of secondary changes in fibro-osseous lesions critically are evaluated.
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