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Targeted Muscle Reinnervation: Surgical Protocol for a Randomized Controlled Trial in Postamputation Pain

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Published on: March 8, 2024

Nontraumatic amputation: incidence and cost analysis.

Ayad Jindeel¹, Kenneth A Narahara

¹Harbor-UCLA Medical Center, Torrance, CA, USA. aj1med@aol.com

The International Journal of Lower Extremity Wounds

|August 7, 2012

Summary

Lower extremity amputation (LEA) remains a significant concern, with high mortality and economic costs. Multidisciplinary foot care is urgently needed to reduce amputation rates.

Area of Science:

Medical Research
Public Health
Health Economics

Background:

Lower extremity amputation (LEA) significantly impacts patients and healthcare costs, despite an overall declining incidence.
This study aimed to analyze nontraumatic LEA at Harbor-UCLA Medical Center (HUMC) from 2000-2007, focusing on mortality and financial burden.

Observation:

The study identified 1169 admissions for nontraumatic LEA in 847 patients.
1-year mortality was 9.1%, and 5-year mortality was 25.6%.
Major amputation and increasing age were independent risk factors for 1-year mortality.

Findings:

The 1-year re-amputation rate was 26.7%.
African American and Hispanic females experienced higher rates of major amputations.
Nontraumatic LEA admissions averaged 12.7 hospital days, more than double the average for all admissions, with an estimated cost of over $47 million.

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Implications:

Nontraumatic LEA poses a substantial mortality risk and economic burden.
Urgent implementation of multidisciplinary foot care clinics is recommended to reduce amputation rates.