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Related Concept Videos

Glaucoma: Overview01:25

Glaucoma: Overview

Glaucoma is an eye condition characterized by increased intraocular pressure that damages the retina and optic nerve, leading to irreversible blindness if left untreated. The human eye has various components, including the cornea, iris, pupil, lens, and optic nerve. Aqueous humor is secreted by the epithelium of the ciliary body in the posterior chamber and flows through the trabecular meshwork and canal of Schlemm, maintaining normal intraocular pressure. The trabecular meshwork and the canal...
Open Angle Glaucoma: Treatment01:27

Open Angle Glaucoma: Treatment

In open-angle glaucoma, the iridocorneal angle remains open, but the trabecular meshwork becomes stiff, slowing down the outflow of aqueous humor. This causes a buildup of aqueous humor in the anterior chamber, leading to a sudden increase in intraocular pressure. The treatment for open-angle glaucoma focuses on reducing the elevated intraocular pressure by either decreasing the secretion of aqueous humor or increasing its outflow.
Drugs such as carbonic anhydrase inhibitors, α2- and...
Angle Closure Glaucoma: Treatment01:28

Angle Closure Glaucoma: Treatment

Angle-closure glaucoma, or closed-angle glaucoma, is an eye condition where the iris bulges out and blocks the iridocorneal angle, resulting in a buildup of aqueous humor and increased intraocular pressure. Immediate medical attention is necessary due to the sudden onset of symptoms. The treatment for angle-closure glaucoma includes short-term and long-term approaches. Short-term treatment involves using eye drops like pilocarpine to lower intraocular pressure by increasing aqueous humor...

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Related Experiment Video

Updated: May 19, 2026

Anterior Segment Organ Culture Platform for Tracking Open Globe Injuries and Therapeutic Performance
07:27

Anterior Segment Organ Culture Platform for Tracking Open Globe Injuries and Therapeutic Performance

Published on: August 25, 2021

Visual outcome in open globe injuries.

T Thevi1, Z Mimiwati, S C Reddy

  • 1Department of Ophthalmology, Tengku Ampuan Rahimah Hospital, Klang, Malaysia.

Nepalese Journal of Ophthalmology : a Biannual Peer-Reviewed Academic Journal of the Nepal Ophthalmic Society : NEPJOPH
|August 7, 2012
PubMed
Summary
This summary is machine-generated.

Good initial vision and shorter corneal lacerations (less than 5mm) predict better visual outcomes after open globe eye injuries. Factors like age, gender, and injury source did not significantly impact results.

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Area of Science:

  • Ophthalmology
  • Trauma Surgery

Background:

  • Open globe injuries represent a significant cause of vision loss.
  • Identifying factors influencing visual outcomes is crucial for patient management.

Purpose of the Study:

  • To identify predictors of visual outcome in patients with open globe eye injuries.

Main Methods:

  • Prospective interventional study of 52 patients with open globe injuries.
  • Data collected included demographics, injury characteristics, and initial examination findings.
  • Injuries were classified, and best-corrected visual acuity was assessed postoperatively.

Main Results:

  • Good initial visual acuity (90%) predicted a good final visual outcome.
  • Corneal lacerations <5mm were associated with significantly better visual outcomes.
  • Corneoscleral lacerations correlated with poorer visual outcomes compared to isolated corneal or scleral injuries.

Conclusions:

  • Key predictors for good visual outcome include high initial visual acuity, corneal lacerations under 5mm, deep anterior chamber, and simple lacerations.
  • Age, gender, injury location, object type, hyphema, intraocular foreign body, and safety precautions did not influence the final visual outcome.