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Updated: May 19, 2026
05:32
Embryo Microinjection for Transgenesis in Drosophila
Published on: June 7, 2024
Expanding the genetic code of Drosophila melanogaster
Ambra Bianco1, Fiona M Townsley, Sebastian Greiss
1Medical Research Council Laboratory of Molecular Biology, Cambridge, UK.
Nature Chemical Biology
|August 7, 2012
Abstract
None:
Genetic code expansion for unnatural amino acid mutagenesis has, until recently, been limited to cell culture. We demonstrate the site-specific incorporation of unnatural amino acids into proteins in Drosophila melanogaster at different developmental stages, in specific tissues and in a subset of cells within a tissue. This approach provides a foundation for probing and controlling processes in this established metazoan model organism with a new level of molecular precision.
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