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Published on: January 17, 2011
Atropine sulphate: rescue therapy for pyloric stenosis
Richard Peter Owen1, Sarah L Almond, Gill M E Humphrey
1Department of General Surgery, Arrowe Park Hospital, Liverpool, UK. richowen83@hotmail.com
Insights
Infantile hypertrophic pyloric stenosis (IHPS) can be complicated by incomplete surgery. This case study shows successful non-surgical management of IHPS with incomplete pyloromyotomy using atropine sulfate therapy.
Area of Science:
- Pediatric Surgery
- Gastroenterology
Background:
- Infantile hypertrophic pyloric stenosis (IHPS) causes gastric outlet obstruction, treated surgically with pyloromyotomy.
- Incomplete pyloromyotomy occurs in 0.3% of cases, requiring reoperation.
- Medical management with antimuscarinics is an alternative but often requires prolonged hospitalization.
Purpose of the Study:
- To describe a case of IHPS with incomplete pyloromyotomy.
- To highlight the successful medical management of this complication.
Main Methods:
- A case of IHPS with incomplete pyloromyotomy was identified.
- The patient was treated with atropine sulfate therapy.
Main Results:
- Successful management of IHPS following incomplete pyloromyotomy was achieved with atropine sulfate.
- This approach avoided further surgical intervention.
Conclusions:
- Atropine sulfate therapy is a viable treatment option for IHPS cases complicated by incomplete pyloromyotomy.
- Medical management can offer a less invasive alternative to repeat surgery.
Abstract:
Infantile hypertrophic pyloric stenosis (IHPS) is a common condition which presents with non-bilious vomiting and failure to thrive secondary to gastric outlet obstruction. In the UK, management is by fluid resuscitation followed by pyloromyotomy. Incomplete myotomy complicates 0.3% of cases necessitating further surgery and exposing the patient to further risk. Medical management of IHPS with antimuscarinics to promote pyloric relaxation is a well-described treatment modality that is used as first-line therapy in some countries. The use of this technique is limited by the need for extended hospital admission with parenteral nutrition administration. We describe a case of IHPS complicated by incomplete pyloromyotomy and subsequently managed successfully by atropine sulphate therapy.
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