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Updated: May 19, 2026

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Published on: July 25, 2017
Exploring the endocrine manifestations of DICER1 mutations
Catherine S Choong1, John R Priest, William D Foulkes
1School of Paediatrics and Child Health, University of Western Australia, Princess Margaret Hospital for Children, Subiaco, Western Australia 6008, Australia.
Abstract:
The discovery of each new cancer susceptibility gene answers one set of questions but poses many more. In this article, we outline a recent example: a new cancer syndrome caused by germline mutations in DICER1, responsible for microRNA processing. In particular, we discuss the endocrine manifestations of mutations in this crucial gene.
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