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Updated: May 19, 2026

Single-Molecule Imaging of Nuclear Transport
Published on: June 9, 2010
Seeing single atoms
1University of California at Santa Cruz, Jack Baskin School of Engineering, Santa Cruz, CA 95064, USA. msi@soe.ucsc.edu
Abstract:
New discoveries and ideas often occur at the confluence of events and technologies that allow them to happen. So it was with the first electron microscopic observations of individual atoms at the University of Chicago laboratory of Albert Crewe forty years ago. This paper will describe the technologies developed then, present some of the historical instrumental details and describe the rationale for the designs that came about in that laboratory over a period of about a decade.
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