Related Experiment Video
Updated: May 19, 2026

Modeling Encephalopathy of Prematurity Using Prenatal Hypoxia-ischemia with Intra-amniotic Lipopolysaccharide in Rats
Published on: November 20, 2015
Posterior plagiocephaly
1Department of Neurological Surgery, Division of Pediatric Neurosurgery, Primary Children's Medical Center, University of Utah, Salt Lake City, UT 84113, USA.
Insights
Posterior plagiocephaly, often deformational, has increased since the "Back to Sleep" campaign. Accurate diagnosis differentiating deformational from synostotic plagiocephaly is crucial for appropriate infant treatment.
Area of Science:
- Pediatric medicine
- Craniofacial anomalies
- Public health initiatives
Background:
- Infant cranial asymmetry, or plagiocephaly, stems from abnormal sutural development (synostotic) or external forces (deformational).
- The incidence of posterior plagiocephaly has significantly risen following the 'Back to Sleep' campaign for sudden infant death syndrome prevention.
Purpose of the Study:
- To differentiate between deformational and synostotic plagiocephaly.
- To highlight diagnostic methods and treatment implications for infant cranial asymmetry.
Main Methods:
- Clinical examination and radiological imaging, including computed tomography (CT), are essential for diagnosis.
- Review of clinical features and diagnostic modalities for posterior plagiocephaly.
Main Results:
- Deformational plagiocephaly constitutes the majority of recent posterior plagiocephaly cases.
- Accurate differentiation is critical as treatments differ significantly: conservative for deformational, surgical for synostotic.
Conclusions:
- While often benign, increased plagiocephaly cases warrant vigilance for potential developmental issues.
- Prompt and accurate diagnosis ensures appropriate management, distinguishing between positional molding and craniosynostosis.
Introduction:
Asymmetrical cranial vaults resulting from external forces on an infant's head can be caused by abnormal sutural development (synostotic plagiocephaly) or abnormal external forces acting on an intrinsically normal, developing cranium (deformational plagiocephaly).
Discussion:
The incidence of posterior plagiocephaly has increased dramatically since the initiation of the "Back to Sleep" campaign against sudden infant death syndrome. The majority of cases are due to deformational plagiocephaly, but rigorous diagnostic evaluation including physical examination and radiological imaging must be undertaken to rule out lambdoid synostosis in extreme or refractory cases.
Conclusion:
Unique clinical features and radiological examination using computed tomography technology are helpful in confirming the correct cause of posterior plagiocephaly. Plagiocephaly is considered a benign condition, but with the recent increase in cases, new studies have revealed developmental problems associated with cranial vault asymmetries. Treatment of positional/deformational plagiocephaly includes conservative measures, primarily behavior modification, and, in some cases, helmet therapy, whereas lambdoid synostotic plagiocephaly requires surgical intervention, making differentiation of the cause of the asymmetry critical.
Related Concept Videos
Cranial Bones: Superior and Posterior View
The frontal bone is the single bone that forms the forehead. At its anterior midline, between the eyebrows, there is a slight depression called the glabella. The frontal bone also forms the supraorbital margin of the orbit. Near the middle of this margin is the supraorbital foramen, the opening that provides passage for a sensory nerve to the forehead. The frontal bone is thickened just above each supraorbital margin,...
Sutures of the Skull
Sutures are immobile joints between adjacent bones of the skull. The narrow gap between the bones is filled with dense, fibrous connective tissue that unites the bones. The long sutures located between the skull bones are not straight but instead follow irregular, tightly twisting paths. These twisting lines tightly...
Neurulation
Cranial Bones: Lateral View
The temporal bone forms the lower lateral side of the skull. The temporal bone is subdivided into several regions. The flattened upper portion is the squamous portion of the temporal bone. Below this area and projecting anteriorly is the zygomatic process of the temporal bone, which forms the posterior portion of the zygomatic arch. Posteriorly is the mastoid portion of the temporal bone. Projecting...
