Search research articles

ABOUT JoVE

Overview Leadership Blog JoVE Help Center

AUTHORS

Publishing Process Editorial Board Scope & Policies Peer Review FAQ Submit

LIBRARIANS

Testimonials Subscriptions Access Resources Library Advisory Board FAQ

RESEARCH

JoVE Journal Methods Collections JoVE Encyclopedia of Experiments Archive

EDUCATION

JoVE Core JoVE Business JoVE Science Education JoVE Lab Manual Faculty Resource Center Faculty Site

Terms & Conditions of Use

Search research articles

Related Experiment Video

Updated: May 19, 2026

Finite Element Modelling of a Cellular Electric Microenvironment

Finite Element Modelling of a Cellular Electric Microenvironment

Published on: May 18, 2021

Electrical stimulation: a novel tool for tissue engineering.

Richard Balint¹, Nigel J Cassidy, Sarah H Cartmell

¹Materials Science Centre, University of Manchester, Manchester, United Kingdom.

Tissue Engineering. Part B, Reviews

|August 10, 2012

Summary

This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by

Same author

Electrical characterisation of conductive hydrogels for biomedical applications.

Acta biomaterialia·2025

Same author

X-Ray Exposure Induces Structural Changes in Human Breast Proteins.

International journal of molecular sciences·2025

Same author

Co-stimulation with piezoelectric PVDF films and low intensity pulsed ultrasound enhances osteogenic differentiation.

Biomaterials advances·2025

Same author

Impact of therapeutic X-ray exposure on collagen I and associated proteins.

Acta biomaterialia·2025

Same author

The Application of High-Resolution, Embedded Fibre Optic (FO) Sensing for Large-Diameter Composite Steel/Plastic Pipeline Performance under Dynamic Transport Loads.

Sensors (Basel, Switzerland)·2024

Same author

Automated fabrication of a scalable heart-on-a-chip device by 3D printing of thermoplastic elastomer nanocomposite and hot embossing.

Bioactive materials·2023

Same journal

Photobiomodulation Targets Mitochondrial Homeostasis for Diabetic Wound Healing.

Tissue engineering. Part B, Reviews·2026

Same journal

Nanotechnology-Driven Noninvasive and Targeted Therapies for Anaplastic Thyroid Carcinoma.

Tissue engineering. Part B, Reviews·2026

Same journal

From Restoration to Regeneration: A Review of 3D Printing Strategies in Digital Dentistry.

Tissue engineering. Part B, Reviews·2026

Same journal

Molecular Pathogenesis of and Regenerative Strategies for Osteonecrosis of the Femoral Head.

Tissue engineering. Part B, Reviews·2026

Same journal

Regenerative Potential of Platelet-Rich Plasma-Loaded Scaffolds in Endometrial Damage: A Meta-Analysis.

Tissue engineering. Part B, Reviews·2026

Same journal

Enhancing Round Window Membrane Permeability for Inner Ear Drug Delivery: A Systematic Review.

Tissue engineering. Part B, Reviews·2026

See all related articles

Electrical stimulation shows promise for tissue engineering, influencing cell behavior for better regeneration. This review explores its natural role and potential applications in developing improved tissue-engineered products.

Area of Science:

Biomedical Engineering
Regenerative Medicine
Cell Biology

Background:

Tissue engineering advances utilize growth factors, biomaterials, and bioreactors to enhance engineered tissues.
Electrical stimulation is crucial for human tissue physiology and development, yet its role in tissue engineering remains underexplored.
Existing methods focus on chemical and physical stimuli, overlooking the potential of endogenous electrical cues.

Purpose of the Study:

To highlight the significance of endogenous electrical stimulation in tissue regeneration.
To consolidate current knowledge on the in vivo occurrence and function of electrical stimuli.
To evaluate the potential benefits of electrical stimulation for the future of tissue engineering.

Main Methods:

Review of existing literature on endogenous electrical stimulation and its effects on cells and tissues.

More Related Videos

Electric and Magnetic Field Devices for Stimulation of Biological Tissues

Electric and Magnetic Field Devices for Stimulation of Biological Tissues

Published on: May 15, 2021

Simultaneous Electrical and Mechanical Stimulation to Enhance Cells' Cardiomyogenic Potential

Simultaneous Electrical and Mechanical Stimulation to Enhance Cells' Cardiomyogenic Potential

Published on: January 18, 2019

Related Experiment Videos

Last Updated: May 19, 2026

Finite Element Modelling of a Cellular Electric Microenvironment

Finite Element Modelling of a Cellular Electric Microenvironment

Published on: May 18, 2021

Electric and Magnetic Field Devices for Stimulation of Biological Tissues

Electric and Magnetic Field Devices for Stimulation of Biological Tissues

Published on: May 15, 2021

Simultaneous Electrical and Mechanical Stimulation to Enhance Cells' Cardiomyogenic Potential

Simultaneous Electrical and Mechanical Stimulation to Enhance Cells' Cardiomyogenic Potential

Published on: January 18, 2019

Analysis of novel methods for delivering electrical stimuli in tissue engineering applications.

Examination of cellular responses, including migration, orientation, proliferation, and differentiation, to electrical cues.

Main Results:

Electrical stimulation plays a vital role in natural tissue development and regeneration.
Specific methods for applying electrical stimuli can modulate cell behavior beneficially.
Understanding endogenous electrical fields can guide the development of more effective tissue regeneration strategies.

Conclusions:

Electrical stimulation is a powerful, underutilized tool for advancing tissue engineering.
Further research into electrical stimulation's mechanisms and applications can significantly improve engineered tissue function.
Integrating electrical cues into tissue engineering protocols holds great promise for regenerative medicine.