Related Experiment Video
Updated: May 19, 2026
07:35
Behavioral Characterization of Pentylenetetrazole-induced Seizures: Moving Beyond the Racine Scale
Published on: July 8, 2025
[Quetiapine and the potential for abuse]
Erlend Aa1, Arne Helland, Olav Spigset
1RELIS Midt-Norge, Avdeling for klinisk farmakologi, St. Olavs hospital, Norway. erlend.aa@legemidler.no
Summary
Quetiapine, an atypical antipsychotic, treats schizophrenia, bipolar disorder, and unipolar depression. However, case reports indicate a potential for quetiapine abuse, particularly in individuals with a history of substance abuse.
Area of Science:
- Pharmacology
- Psychiatry
- Neuroscience
Context:
- Quetiapine is an established atypical antipsychotic.
- It is prescribed for schizophrenia, bipolar disorder, and as an adjunct for unipolar depression.
Purpose:
- To summarize the known therapeutic applications of quetiapine.
- To highlight emerging concerns regarding its potential for drug abuse.
Summary:
- Quetiapine is licensed for schizophrenia, bipolar disorder, and adjunctive treatment of unipolar depression.
- Case reports suggest a risk of quetiapine abuse.
- This risk appears elevated in individuals with a history of substance abuse.
Impact:
- Informs clinicians about the dual nature of quetiapine: therapeutic benefits and abuse potential.
- Raises awareness for monitoring patients at risk of substance abuse.
- Contributes to the understanding of atypical antipsychotic misuse.
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