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A Semi-Automated and Reproducible Biological-Based Method to Quantify Calcium Deposition In Vitro
Published on: June 2, 2022
Calcium metabolism and correcting calcium deficiencies
Ronald D Emkey1, Gregory R Emkey
1Pennsylvania Regional Center for Arthritis & Osteoporosis Research, 1200 Broadcasting Road, Suite 200, Wyomissing, PA 19610, USA. bonedocron@yahoo.com
Endocrinology and Metabolism Clinics of North America
|August 11, 2012
Summary
Understanding calcium absorption and needs is crucial for bone health. This review details calcium
Area of Science:
- Biochemistry
- Physiology
- Nutrition Science
Background:
- Calcium (Ca) is the most abundant cation in the human body.
- Approximately 99% of Ca is found in bone, providing structural integrity.
- Bone serves as a reservoir for Ca essential for physiological processes.
Purpose of the Study:
- To provide a comprehensive understanding of Ca absorptive mechanisms.
- To identify factors influencing Ca absorption.
- To establish Ca needs and provide rationale for correcting deficiencies.
Main Methods:
- Literature review of Ca absorption and metabolism.
- Analysis of factors affecting Ca bioavailability.
- Review of Ca requirements, dosing, preparations, and toxicities.
Main Results:
- Detailed explanation of Ca absorptive pathways.
- Identification of key factors influencing Ca uptake.
- Overview of Ca requirements and therapeutic considerations.
Conclusions:
- Adequate Ca absorption is vital for bone health and overall physiology.
- Understanding Ca needs and absorption mechanisms aids in deficiency correction.
- Proper Ca supplementation requires knowledge of preparations and potential toxicities.
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