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Updated: May 19, 2026
A Model of Glaucoma Induced by Circumlimbal Suture in Rats and Mice
Published on: October 5, 2018
Modelling postoperative visual acuity with and without proliferative vitreoretinopathy associated with primary
M Roldán-Pallarés1, C Bravo-Llatas, A-S Musa
1Department of Ophthalmology, Medical School, Complutense University, 28008 Madrid, Spain. MRPUCMHS@telefonica.net
Purpose:
To find models that will explain the variability in postoperative visual acuity (VA) (logarithmic: logMAR) associated with unilateral primary rhegmatogenous retinal detachment (RD).
Methods:
This was a prospective clinical cohort study of 33 patients with proliferative vitreoretinopathy (PVR: PVR
Results:
The models for 8-month-postoperative logMAR VA demonstrated a predictive power higher than 85%. The values of the 8-month-postoperative logMAR VA were as follows: (a) in No PVR= -0.151+0.06 preoperative duration (days), with a predictive power of 85.3%; (b) in PVR= -1.071+0.06 SRF IR-ET-1 (pg/ml)+0.459 preoperative logMAR VA explaining 89.9% of the variability in the postoperative logMAR VA.
Conclusions:
The duration of RD and the levels of IR-ET-1 in the SRF appear to be the best explanatory variables in the models for 8-month-postoperative logMAR VA variability in RD patients. RD surgery should be performed as soon as possible to best preserve VA.
