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Mechanical Micronization of Lipoaspirates for Regenerative Therapy
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Nanotechnology in plastic surgery.

Ahmed M S Ibrahim1, Theodore L Gerstle, Amr N Rabie

  • 1Boston and Cambridge, Mass. From the Division of Plastic Surgery, Beth Israel Deaconess Medical Center, Harvard Medical School, and the Departments of Biological Engineering and Electrical Engineering and Computer Sciences, Massachusetts Institute of Technology.

Plastic and Reconstructive Surgery
|August 11, 2012
PubMed
Summary
This summary is machine-generated.

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Microelectromechanical systems (MEMS) nanotechnology offers new ways to modulate nerve impulses. This innovation may advance plastic surgery by improving healing, infection control, and nerve regeneration.

Area of Science:

  • Biomedical Engineering
  • Nanotechnology
  • Plastic Surgery

Background:

  • Nanotechnology is increasingly integrated into surgical and medical applications.
  • Microelectromechanical systems (MEMS) enable miniaturized implants for various clinical conditions.
  • The potential of nanotechnology in plastic surgery is significant and evolving.

Purpose of the Study:

  • To investigate a MEMS-based electrochemical stimulation method for modulating nerve ion concentrations.
  • To explore current and potential applications of nanotechnology in plastic surgery.
  • To review existing literature on nanotechnology in medicine.

Main Methods:

  • Electrical stimulation of sciatic nerves in American bullfrogs using a microfabricated gold electrode array.

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  • In situ modulation of ion concentrations around the nerve using Ca(2+)-selective membranes.
  • Comprehensive literature review on nanotechnology in medicine.

    • Main Results:

    • A 40% reduction in the electrical threshold value was achieved with the Ca(2+) ion-selective membrane.
    • Specific applications of nanotechnology relevant to plastic surgery were identified and detailed.

    Conclusions:

    • MEMS nanotechnology provides a novel method for modulating nerve impulse activation.
    • These findings suggest potential for nano-enhanced materials in plastic surgery for healing, infection control, and nerve regeneration.
    • Nanotechnology is poised to drive advancements in plastic surgery.