Related Experiment Video
Updated: May 19, 2026

An Orthotopic Mouse Model of Anaplastic Thyroid Carcinoma
Published on: April 17, 2013
Thymoma hyalinized by steroid therapy in myasthenia gravis
Yukihiro Yoshida1, Ryuta Ueda, Tomohiro Murakawa
1Department of Cardiothoracic Surgery, The University of Tokyo, Graduate School of Medicine, and Department of Neurology, Mita Hospital, Tokyo, Japan. yyoshida-tky@umin.ac.jp
Abstract:
We encountered a 72-year-old woman with myasthenia gravis and thymoma who received glucocorticoid therapy for respiratory failure before undergoing thymectomy. After the antiacetylcholine receptor antibody titer was normalized, and the thymoma shrunk with prednisolone, the patient was free from symptoms. On pathological examination, the majority of the thymoma (type B2) had been hyalinized. Preoperative steroid therapy was effective in stabilizing myasthenia gravis and in inducing apoptosis of both epithelial and lymphocytic components of the thymoma.
Related Concept Videos
Myasthenia Gravis: Overview and Treatment
These antibodies interfere with the function of the nicotinic receptors in three ways: by binding to the receptor and disrupting acetylcholine binding; by causing cross-linking of receptors which leads...
Myasthenia Gravis ll: Pathophysiology
Myasthenia Gravis: Diagnostic Tests
The edrophonium test is a diagnostic tool for myasthenia gravis. It involves...
Graves Disease II: Pathophysiology
Hyperthyroidism II: Pathophysiology
Graves' Disease I: Introduction