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Behavioural fever boosts the inflammatory response in rainbow trout Oncorhynchus mykiss
A Gräns1, M Rosengren, L Niklasson
1Department of Biological and Environmental Sciences, University of Gothenburg, Medicinaregatan 18, Box 463, 405 30 Gothenburg, Sweden. albin.grans@bioenv.gu.se
Abstract:
Behavioural fever, manifested as an increased preferred temperature, was shown in rainbow trout Oncorhynchus mykiss following an injection of bacterial lipopolysaccharide. Simulated behavioural fever, through a 2·5° C water temperature rise following bacterial lipopolysaccharide injection, enhanced the expression of the cytokine interleukin-1β, in comparison with an untreated group held at the initial temperature. The present findings show that an important mediator in the immune response can be boosted through behavioural fever in fishes.
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