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Nail disorders as signs of pediatric systemic disease
1Division of Pediatric Dermatology, Cincinnati Children's Hospital, Cincinnati, Ohio, USA.
Insights
Pediatric nail changes can indicate systemic diseases in children. A thorough physical exam and family history are crucial for diagnosing nail disorders and identifying underlying conditions.
Area of Science:
- Pediatric Dermatology
- Systemic Disease Manifestations
Background:
- Nail changes in children can be indicators of underlying systemic diseases.
- Differentiating systemic causes from local nail unit disorders is clinically important.
Purpose of the Study:
- To describe common nail unit changes associated with systemic diseases in pediatric patients.
- To emphasize the diagnostic value of nail examination in conjunction with other clinical findings.
Main Methods:
- Review of common nail changes observed in pediatric systemic diseases.
- Emphasis on clinical examination of skin, oral mucosa, and family history.
Main Results:
- Multiple nail changes in an ill child often suggest a systemic cause.
- Primary inflammatory disorders and infections can also affect multiple nails.
Conclusions:
- Nail unit examination is a valuable diagnostic tool in pediatric healthcare.
- Integration of nail findings with dermatological, mucosal, and familial data aids in diagnosing systemic conditions.
Abstract:
Herein, we describe some of the more common changes in the nail unit that can be seen in systemic diseases in children. Changes that can be seen are not limited to those discussed in the following pages. The presence of changes on multiple nails is suggestive of a systemic cause in an ill child. However, multiple nails can also be affected in primary inflammatory disorders and infections of the nail unit. When evaluating a pediatric patient with a nail disorder, it is important to perform a complete physical examination of the skin and oral mucosa, as other clues to the diagnosis of the nail problem may be found. A comprehensive family history is also important to uncover possible syndromic associations with nail disease or diseases that can manifest with nail changes.
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