[The use of clopheline in premedication]

Central and peripheral hemodynamic changes have been studied in 80 patients aged 18 to 67 years after planned gastro-intestinal and biliary surgery. In 40 of them clopheline (clonidine) was used in premedication. The use of clopheline in premedication led to stabilization of central hemodynamic parameters, made it possible to improve considerably microcirculation, avoid the unfavourable effects of psychic tension, induction to anesthesia, laryngoscopy and tracheal intubation. All the above permits the authors to recommend the use of clopheline in premedication.