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Related Concept Videos

Seizures: Classification01:13

Seizures: Classification

Epilepsy is primarily characterized by unpredictable seizures, either provoked by an identifiable factor, such as injury or illness, or unprovoked, occurring spontaneously without apparent cause.
Seizures are typically classified into two main categories: focal and generalized seizures.
Focal Seizures
Focal seizures originate from specific regions of the brain. These seizures are further sub-classified into two types:
Seizures l: Introduction01:20

Seizures l: Introduction

Understanding seizures and epilepsy relies on key definitions that help in recognizing, classifying, and managing these disorders. These definitions provide a framework for recognizing, classifying, and managing seizure disorders.DefinitionsA seizure is a sudden, abnormal burst of electrical activity in the brain that can cause changes in awareness, movement, sensation, or behavior, depending on the area involved. Epilepsy is a chronic condition characterized by recurrent, unprovoked seizures,...
Epilepsy ll: Types01:22

Epilepsy ll: Types

Recurrent seizures, stemming from abnormal electrical activity in the brain, are the defining characteristic of epilepsy, a chronic neurological condition. Because seizure features vary greatly, epilepsy is classified using two systems: by seizure type and by epilepsy syndromes. These classifications enable clinicians to describe seizure patterns and select suitable treatment strategies.I. Classification by Seizure Type1. Focal EpilepsyFocal epilepsy begins in one hemisphere of the brain.
Epilepsy and Seizures: Overview01:24

Epilepsy and Seizures: Overview

Epilepsy is a chronic neurological disease marked by recurrent, unpredictable seizures. These seizures are caused by abnormal electrical discharges in the brain, leading to behavior, sensation, or consciousness alterations. They can also cause transient impairment of awareness, interfering with daily activities.
Various factors can trigger epilepsy, including genetic factors, brain damage, metabolic causes, and unknown etiology. Diagnosis of epilepsy involves electroencephalography (EEG), which...
Drug Dosing: Geriatric Patients01:15

Drug Dosing: Geriatric Patients

Elderly individuals encompass a diverse population with varying degrees of age-related physiological changes. Defining the elderly presents challenges, as the geriatric population is often arbitrarily categorized as individuals older than 65. However, many individuals in this group lead active and healthy lives, with an increasing number surpassing 85 years and falling into the older elderly category. Physiological changes associated with aging impact performance capacity and homeostatic...
Pharmacokinetics in Geriatric Patients: Effect of Age on Drug Excretion01:18

Pharmacokinetics in Geriatric Patients: Effect of Age on Drug Excretion

In geriatric patients, renal physiology undergoes significant changes, including diminished renal blood flow and a lower glomerular filtration rate (GFR), leading to alterations in medication clearance. Drugs such as aminoglycoside antibiotics, lithium, and digoxin, which rely on glomerular filtration for removal from the body, particularly impact pharmacokinetics. These drugs tend to have slower clearance rates in older adults, necessitating careful dosage considerations.Evaluation of renal...

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Related Experiment Video

Updated: May 19, 2026

Methods for ECG Evaluation of Indicators of Cardiac Risk, and Susceptibility to Aconitine-induced Arrhythmias in Rats Following Status Epilepticus
08:28

Methods for ECG Evaluation of Indicators of Cardiac Risk, and Susceptibility to Aconitine-induced Arrhythmias in Rats Following Status Epilepticus

Published on: April 5, 2011

Nonconvulsive status epilepticus in elderly a possible diagnostic pitfall.

Linda Shavit1, Tal Grenader, Ilia Galperin

  • 1Division of Internal Medicine and Geriatric Department, Shaare Zedek Medical Center, Jerusalem, Israel. lshavit@szmc.org.il

European Journal of Internal Medicine
|August 14, 2012
PubMed
Summary

Nonconvulsive status epilepticus (NCSE) is often missed in the elderly. Prompt diagnosis with EEG and anticonvulsant treatment significantly improves mental status in older patients with NCSE.

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Methods for ECG Evaluation of Indicators of Cardiac Risk, and Susceptibility to Aconitine-induced Arrhythmias in Rats Following Status Epilepticus
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Published on: July 21, 2015

Area of Science:

  • Neurology
  • Geriatrics

Background:

  • Nonconvulsive status epilepticus (NCSE) presents with subtle behavioral changes, often missed in the elderly.
  • Varied clinical presentations of NCSE contribute to diagnostic challenges.

Purpose of the Study:

  • To determine the prevalence, clinical characteristics, treatment, and outcomes of NCSE in geriatric patients.
  • To highlight the importance of recognizing NCSE in older adults.

Main Methods:

  • Prospective data collection from geriatric inpatients with unexplained mental status changes.
  • Diagnosis of NCSE confirmed by characteristic EEG findings and improvement after anticonvulsant therapy.

Main Results:

  • 14 elderly patients (mean age 81) diagnosed with NCSE.
  • All patients exhibited altered consciousness (confusion, coma, stupor).
  • Anticonvulsant therapy led to prompt and significant improvement in EEG and mental status.

Conclusions:

  • High clinical suspicion and EEG are crucial for diagnosing NCSE in the elderly.
  • Anticonvulsant therapy offers significant benefits for elderly patients with NCSE, even with comorbidities.
  • EEG is vital for evaluating acute mental changes in the elderly, identifying this treatable condition.