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Updated: May 19, 2026
In Vitro Differentiation Model of Human Normal Memory B Cells to Long-lived Plasma Cells
Published on: January 20, 2019
A rare case of plasma cell leukemia in a 35 year old
Rupal V Dosi1, Annirudh Ambaliya, Rushad D Patell
1Department of Medicine, Government Medical College and S. S. G. Hospital, Vadodara, Gujarat, India.
Abstract:
Plasma cell leukemia is a rare, aggressive form of multiple myeloma. A 35-year-old male presented with backache, generalized weakness, and facial puffiness. His complete blood count showed anemia and a high WBC count with atypical cells on peripheral smear. Bone marrow examination showed more than 90% of atypical plasma cells, confirming a diagnosis of plasma cell leukemia. Patient also had azotemia, hypercalcemia, and hyperuricemia. The patient was started on chemotherapy along with supportive care. Patient improved dramatically and he was discharged on regular follow-up.
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