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Synthesis, structure, and reactivity of borole-functionalized ferrocenes

Holger Braunschweig1, Ching-Wen Chiu, Daniela Gamon

  • 1Institut für Anorganische Chemie, Julius-Maximilians Universität Würzburg, Am Hubland, 97074 Würzburg, Germany. h.braunschweig@uni-wuerzburg.de

Chemistry (Weinheim an Der Bergstrasse, Germany)
|August 14, 2012
PubMed

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In addition to the oxymercuration–demercuration method, which converts the alkenes to alcohols with Markovnikov orientation, a complementary hydroboration-oxidation method yields the anti-Markovnikov product. The hydroboration reaction, discovered in 1959 by H.C. Brown, involves the addition of a B–H bond of borane to an alkene giving an organoborane intermediate. The oxidation of this intermediate with basic hydrogen peroxide forms an alcohol.
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