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Fungal Phylum Basidiomycota

Fungal Phylum Basidiomycota

Basidiomycota is a diverse phylum of fungi that includes ecologically significant decomposers such as white rot fungi, symbionts like mycorrhizal fungi, plant pathogens such as rusts and smuts, and edible species like Agaricus bisporus (the common button mushroom). These fungi play crucial roles in nutrient cycling, symbiotic relationships, and even human health. Their defining feature is the basidium, a microscopic club-shaped structure responsible for producing basidiospores.Fruiting Bodies...

Fungal Group Zygomycota

Fungal Group Zygomycota

Zygomycota, previously classified as a distinct fungal group, are primarily terrestrial, saprophytic molds that play a crucial role as decomposers. Recent phylogenetic studies have revealed that these fungi are now divided into two major clades — Mucoromycota, which includes many symbiotic species, and Zoopagomycota, which primarily consists of parasitic and pathogenic fungi. These groups exhibit distinct ecological roles and reproductive strategies while sharing key structural and...

Fungal Phylum Microsporidia

Fungal Phylum Microsporidia

Microsporidia are a group of obligate intracellular fungi that were initially classified as protists but were later reclassified based on phylogenetic, molecular, and structural evidence linking them to the Chytridiomycota. These unicellular, non-motile organisms are highly specialized parasites that infect a wide range of animal hosts, including humans. They have evolved extensive genomic and metabolic reductions, making them highly dependent on their hosts for survival.Morphology and Genomic...

Fungal Phylum Ascomycota

Fungal Phylum Ascomycota

Phylum Ascomycota, a major division within the subkingdom Dikarya, comprises a diverse range of fungal species, including both unicellular yeasts and filamentous molds such as Aspergillus and Penicillium. These fungi thrive in a variety of habitats, from aquatic ecosystems to terrestrial environments, playing crucial ecological and economic roles.Morphology and ReproductionThe defining characteristic of Ascomycetes, commonly referred to as sac fungi, is the ascus—a sac-like structure that...

Overview of Fungi

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Fungi are a diverse group of eukaryotes more closely related to animals than other eukaryotes. Fungal cell walls comprise chitin, a polysaccharide that provides structural strength, and glucans, which contribute to flexibility and integrity. Other polysaccharides, such as mannans and galactosans, may supplement or replace chitin in some fungi. These adaptations, along with their preference for acidic environments and tolerance for high osmotic pressure, enable fungi to thrive in various...

Antifungal Agents

Antifungal Agents

Amphotericin B is a broad-spectrum antifungal agent that exploits structural differences between fungal and mammalian cell membranes. Its amphipathic structure—featuring a hydrophobic polyene-lactone ring and a hydrophilic region containing mycosamine and carboxylic acid groups—enables selective binding to ergosterol, a sterol predominantly found in fungal plasma membranes. This selective interaction underlies the drug’s antifungal activity, although weak binding to cholesterol contributes to...

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Updated: May 19, 2026

Sexual Crosses with the Mucoromycete Phycomyces blakesleeanus

Sexual Crosses with the Mucoromycete Phycomyces blakesleeanus

Published on: June 6, 2025

[Basidiobolomycosis: a review].

K Kombaté¹, B Saka, A Mouhari-Toure

¹Service de Dermatologie et Infections Sexuellement Transmissibles, CHU Tokoin, Université de Lomé, Togo.

Medecine Et Sante Tropicales

|August 15, 2012

Summary

This summary is machine-generated.

Basidiobolomycosis, a fungal infection, primarily affects children and presents as subcutaneous plaques. Azole derivatives are effective treatments, offering a better safety profile than older therapies.

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Area of Science:

Mycology
Infectious Diseases
Dermatology

Context:

Review of 89 articles (1970-2010) on basidiobolomycosis.
Analysis of 172 cases from global literature, with a focus on Asia and Africa.
Identification of basidiobolomycosis as a significant pediatric infection.

Purpose:

To comprehensively review the literature on basidiobolomycosis.
To describe the epidemiology, clinical presentation, and treatment of basidiobolomycosis.
To evaluate the efficacy and safety of various treatment modalities.

Summary:

Basidiobolomycosis is a fungal infection predominantly affecting individuals under 15 years old, with a male predominance (M/F ratio 2.1).
Clinical manifestations include firm, circumscribed subcutaneous plaques, which can progress to invasive gastrointestinal or pulmonary disease, or systemic dissemination.
Treatment options include potassium iodide, trimethoprim-sulfamethoxazole, and azole derivatives, with azoles demonstrating superior efficacy and tolerability.

Impact:

Highlights the global distribution and epidemiological trends of basidiobolomycosis.
Provides insights into the clinical spectrum and diagnostic considerations for this mycosis.
Recommends azole derivatives as a preferred treatment option due to their effectiveness and safety profile.