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Updated: Jan 1, 2026

Inducing Meningococcal Meningitis Serogroup C in Mice via Intracisternal Delivery

Inducing Meningococcal Meningitis Serogroup C in Mice via Intracisternal Delivery

Published on: November 5, 2019

Meningitis trends in Niger 2008-2015: a secondary data analysis.

I Djibo¹, P K Yanogo², J Kaboré³

¹Programme ouest-africain de formation en épidémiologie, Burkina Faso.

Medecine Et Sante Tropicales

|December 31, 2019

Summary

Meningitis epidemics in Niger are primarily caused by Neisseria meningitidis, Streptococcus pneumoniae, and Haemophilus influenzae. The study highlights the emergence of Neisseria meningitidis serogroup C, recommending targeted vaccination strategies.

Keywords:

Haemophilus Influenzae Meningitis Neisseria meningitidis Niger Streptococcus pneumoniae

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Neisseria meningitidis Infection of Induced Pluripotent Stem-Cell Derived Brain Endothelial Cells

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Published on: July 14, 2020

Area of Science:

Epidemiology
Infectious Diseases
Public Health

Background:

Niger is situated in the meningitis belt, experiencing recurring epidemics.
Meningitis outbreaks in the region exhibit significant annual variability.

Purpose of the Study:

To analyze meningitis trends in Niger from 2008 to 2015.
To identify the microbial agents responsible for meningitis epidemics in Niger.

Main Methods:

A descriptive study utilizing secondary analysis of meningitis data.
Inclusion of all suspected and confirmed meningitis cases reported in Niger between 2008 and 2015.
Exhaustive sampling of the study population.

Main Results:

6,167 confirmed meningitis cases were identified.
Neisseria meningitidis accounted for 89.3% of cases, followed by Streptococcus pneumoniae (9.6%) and Haemophilus influenzae (1.1%).
Among Neisseria meningitidis cases, serogroup A was most prevalent (54.2%), with notable proportions of serogroup W (24.2%) and serogroup C (21.1%).

Conclusions:

The study successfully characterized meningitis trends and causative agents in Niger.
An increase in Neisseria meningitidis serogroup C cases was observed.
Vaccination against Neisseria meningitidis serogroup C is recommended.