Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

X-ray Imaging01:24

X-ray Imaging

9.6K
German physicist Wilhelm Röntgen (1845–1923) was experimenting with electrical current when he discovered that a mysterious and invisible "ray" would pass through his flesh but leave an outline of his bones on a screen coated with a metal compound. In 1895, Röntgen made the first durable record of the internal parts of a living human: an "X-ray" image (as it came to be called) of his wife’s hand. Scientists worldwide quickly began their own experiments with...
9.6K
X-ray Crystallography02:18

X-ray Crystallography

25.5K
The size of the unit cell and the arrangement of atoms in a crystal may be determined from measurements of the diffraction of X-rays by the crystal, termed X-ray crystallography.
Diffraction
Diffraction is the change in the direction of travel experienced by an electromagnetic wave when it encounters a physical barrier whose dimensions are comparable to those of the wavelength of the light. X-rays are electromagnetic radiation with wavelengths about as long as the distance between neighboring...
25.5K
Inductively Coupled Plasma Atomic Emission Spectroscopy: Instrumentation01:26

Inductively Coupled Plasma Atomic Emission Spectroscopy: Instrumentation

534
Inductively coupled plasma (ICP) is the common plasma source used in atomic emission spectroscopy (AES), a technique that detects and analyzes various elements in a sample. This method is often called inductively coupled plasma atomic emission spectroscopy (ICP-AES).
There are three main types of inductively coupled plasma atomic emission spectroscopy  (ICP-AES) instruments: sequential, simultaneous multichannel, and Fourier transform instruments, with the latter being less commonly used....
534

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Advancing three-dimensional tendon imaging using laboratory X-ray phase contrast techniques and refined sample preparation.

Scientific reports·2026
Same author

Macromolecular crystallography at Elettra: current and future perspectives. Corrigendum.

Journal of synchrotron radiation·2026
Same author

Three-dimensional high-content imaging of unstained soft tissue with subcellular resolution using a laboratory-based X-ray microscope.

Proceedings of the National Academy of Sciences of the United States of America·2026
Same author

Mapping the Hierarchical Environmental Transformations of Nanoscale UiO-66 Metal-organic Framework.

Environmental science & technology·2026
Same author

Application of Noise2Inverse and adaptation (Noise2Phase) to single-mask x-ray phase contrast micro-computed tomography.

Journal of microscopy·2025
Same author

Simulating light transmission and wavefront shaping in turbid media with a T-matrix method.

Optics express·2025

Related Experiment Videos

Phase and absorption retrieval using incoherent X-ray sources.

Peter R T Munro1, Konstantin Ignatyev, Robert D Speller

  • 1Department of Medical Physics and Bioengineering, University College London, Torrington Place, London WC1E 6BT, United Kingdom. peter.munro@uwa.edu.au

Proceedings of the National Academy of Sciences of the United States of America
|August 15, 2012
PubMed
Summary
This summary is machine-generated.

This study introduces a novel X-ray phase retrieval method using conventional sources. It enables quantitative phase imaging and tomography with reduced radiation dose and exposure time.

Related Experiment Videos

Area of Science:

  • Medical Imaging
  • Materials Science
  • Physics

Background:

  • X-ray absorption imaging has limitations.
  • X-ray phase contrast imaging offers quantitative information for material identification and tissue differentiation.
  • Phase retrieval is crucial for X-ray phase tomography but challenging with conventional, low-coherence X-ray sources.

Purpose of the Study:

  • To develop a truly incoherent phase retrieval method for X-ray imaging.
  • To enable quantitative phase imaging and tomography using conventional X-ray sources without coherence constraints.
  • To overcome limitations of existing phase retrieval techniques regarding source requirements and data acquisition.

Main Methods:

  • A novel, non-interferometric, non-crystal-based phase retrieval technique utilizing the pixel edge illumination principle.
  • Employing a conventional X-ray source without aperturing, collimation, or filtering.
  • Using X-ray masks to create beams, measuring their displacements caused by sample interaction due to source incoherence.

Main Results:

  • Demonstrated a truly incoherent phase retrieval method applicable to conventional X-ray sources.
  • Achieved strong phase contrast and accurate measurement of beam displacements despite source incoherence.
  • Extracted quantitative information from only two images, significantly reducing data requirements compared to coherent methods.

Conclusions:

  • The developed technique makes quantitative phase imaging and phase tomography feasible with conventional sources.
  • This method is suitable for applications where exposure time and radiation dose are critical.
  • The use of commercially available masks allows for a large field of view and high photon energy, promising safer quantitative phase imaging in the future.